Riboflavin (Vitamin B2)

Riboflavin is a water-soluble member of the Vitamin B-Complex, and in the body, Riboflavin is primarily found as an integral component of the coenzymes flavin adenine dinucleotide (“FAD”) and flavin mononucleotide (“FMN”).[1] FAD is part of the electron transport (respiratory) chain, which is central to energy production.

Coenzymes derived from Riboflavin are termed flavocoenzymes, and flavocoenzyme using enzymes are called flavoproteins.[2]

Flavocoenzymes participate in oxidation-reduction (redox) reactions – which living organisms use to derive most of their energy – in numerous metabolic pathways.[3] They are also critical for the metabolism of carbohydrates, fats, and proteins.

Decreased intracellular levels of flavocoenzymes could cause mitochondrial dysfunction, increase oxidative stress, and interfere with nitric oxide release and thus blood vessel dilation.[4]

Riboflavin deficiency has been associated with increased oxidative stress.[5] For example, Riboflavin deficiency can result in decreased xanthine oxidase activity, reducing blood uric acid levels[6] – one of the most effective water-soluble antioxidants in the blood.

Each serving of Elebra contains Riboflavin, and is manufactured in a cGMP facility that has an "A" rating (the highest possible) from the National Nutritional Foods Association. We stand behind our product and offer a 100% Money Back Guarantee.

References
1. Food and Nutrition Board, Institute of Medicine. Riboflavin. Dietary Reference Intakes: Thiamin, Riboflavin,
    Niacin, Vitamin B6, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy
    Press; 1998:87-122.
2. Brody T. Nutritional Biochemistry. 2nd ed. San Diego: Academic Press; 1999.
3. McCormick DB. Riboflavin. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and
    Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:391-399.
4. Wacker J, Fruhauf J, Schulz M, Chiwora FM, Volz J, Becker K. Riboflavin deficiency and preeclampsia. Obstet
    Gynecol. 2000;96(1):38-44.
5. Powers HJ. Current knowledge concerning optimum nutritional status of riboflavin, niacin and pyridoxine. Proc
    Nutr Soc. 1999;58(2):435-440.
6. Bohles H. Antioxidative vitamins in prematurely and maturely born infants. Int J Vitam Nutr Res.
    1997;67(5):321-328.