Phosphatidylserine

A study showed Phosphatidylserine enhanced mood in a cohort of young people during mental stress and to improved accuracy during tee-off by increasing the stress resistance of golfers.[1]

PET imaging of a 59-year-old woman’s brain showed taking 500mg of Phosphatidylserine daily for three weeks increased metabolism in almost all brain regions.[2]

Phosphatidylserine is a component of the cerebral cortex’s neuronal membrane,[3] and helps restore your brain's supply and output of acetylcholine, a neurotransmitter essential to memory.[4] It also helps restore your brain's supply and output of dopamine, which is essential to memory, attention and problem-solving.[5]-[11]

Phosphatidylserine has been shown to enhance mood in a cohort of young people during mental stress.12 One study found preliminary evidence that a combination of soy-based Phosphatidylserine and lecithin may moderate the body's reaction to mental stress.[13]

Phosphatidylserine has also ameliorated elevations of stress hormones associated with strenuous exercise in young men.[14],[15]

Researchers at the University of Milan conducted a study of 10 women with depression, aged 70 to 81 years, and found Phosphatidylserine increased brain turnover of norepinephrine, dopamine, acetylcholine and glucose reserves. Using the Hamilton Rating Scale for Depression (HRSD) and clinical observation, the researchers found treatment with Phosphatidylserine, compared with pre-treatment baseline scores and controls, caused anxiety levels to decrease while improving long-term memory and learning.[16]

Each serving of Elebra contains 100mg of soy-derived Phosphatidylserine, and is manufactured in the USA at a cGMP facility that has an "A" rating (the highest possible) from the National Nutritional Foods Association. We stand behind our product and offer a 100% Money Back Guarantee.

References
1. Jäger R, Purpura M, Geiss KR, Weiß M, Baumeister J, Amatulli F, Schröder L, Herwegen H. (12 2007). "The
    effect of phosphatidylserine on golf performance". Journal of the International Society of Sports Nutrition 4 (1):
    23. doi:10.1186/1550-2783-4-23. PMC 2217563. PMID 18053194
2. Klinkhammer P, Szelies B, Heiss WD. Effect of phosphatidylserine on cerebral glucose metabolism in
    Alzheimer's disease. Dementia. 1990;1(4):197-201.
3. Langelier B, Linard A, Bordat C, Lavialle M, Heberden C. Long chain-polyunsaturated fatty acids modulate
    membrane phospholipids composition and protein localization in lipid rafts of neural stem cell cultures. Cell
    Biochem. 2010;15:1356–1364.
4. M.G.Vannucchi, G. Pepeu. Effect of Phosphatidylserine on Acetylcholine Release and Content in Cortical
    Slices From Aging Rats.Neurobiol Aging 1987, 8(5), 403 – 407.
5. M.G.Vannucchi, F. Casamenti, G. Pepeu.Decrease of acetylcholine release from cortical slices in aged rats:
    investigations into its reversal by Phosphatidylserine. J.Neurochem 1990, 55, 819 – 25.
6. G. Pepeu, L.Giovanelli, M.G. Giovannini, F. Pedata. Effects of Phosphatidylserine on cortical acetylcholine
    release and calcium uptake in adult and aging rats. In Phospholipid research and the nervous system.
    Biochemical and molecular pharmacology. L.A.Horrocks, L. Freysz, G.Toffano (Eds), Liviana Press, Padova,
    1986, 265 – 271.
7. M.G.Vannucchi, F. Casamenti, G. Pepeu.Decrease of Acetylcholine release from cortical slices in aged rats:
    investigations into its reversal by Phosphatidylserine. J. Neurochem. 1990, 55, 819 – 825.
8. F. Casamenti. P.Mantovani, L. Amaducci, G. Pepeu. Effect of phosphatidylserine on acetylcholine output from
    the cerebral cortex of the rat. J. Neurochem 1979, 32, 529 – 533.
9. F. Casamenti, C. Scali, G. Pepeu. Phosphatidylserine reverses the age-dependent decrease in cortical
    acetylcholine release: a microdialysis study, Eur. J. Pharmacol 1991, 194, 11 – 16.
10. F. Pedata, L.Giovannelli, G. Spignoli, M.G. Giovannini, G. Pepeu. Phosphatidylserine increases acetylcholine
    release from cortical slices in aged rats.Neurobiol Aging 1985, 6, 337 – 339.
11. S.Mazzari, A. Battistella. Phosphatidylserine effects on dopamine release from striatum synaptosomes. In:
    Multidisciplinary Approach to Brain Development. C. Benedetta, R. Balazs, G. Gombos, G. Porcellani (Eds.).
    Elsevier/North Holland, Amsterdam, 1980, 569 – 570.
12. Benton D, Donohoe RT, Sillance B, Nabb S: The Influence of phosphatidylserine supplementation on mood
    and heart rate when faced with an acute stressor. Nutr Neurosci 2001, 4(3):169-178.
13. Hellhammer J, Fries E, Buss C, et al. Effects of soy lecithin phosphatidic acid and phosphatidylserine
    complex (PAS) on the endocrine and psychological responses to mental stress. Stress.2004;7:119-126.
14. Monteleone, P, Beinat, L, Tanzillo,C, Maj, M, and Kemali, D. Effects of phosphatidylserine on the
    neuroendocrine response to physical stress in humans. Neuroendocrinol, 1990. 52: 243-8.
15. Monteleone, P, Maj,M, Beinat,L, Natale,M, and Kemali,D. Blunting by chronic phosphatidylserine administration
    of the stress-induced activation of the hypothalamos-pituitary-adrenal axis in healthy men. Eur. J.
    Clin.Pharmacol ,1992. 41: 385-8.
16. Maggioni M, et al. Effects of Phosphatidylserine Therapy in Geriatric Patients With Depressive Disorders. Acta
    Psychiatr Scand 1990;81:265-270.